Polynucleotides: The Future of Skin Rejuvenation in Mumbai
Skin rejuvenation is evolving rapidly — moving beyond fillers and traditional anti-ageing injectables into the world of regenerative dermatology. One of the most exciting innovations is the use of polynucleotides (PNs). Globally, they are being called the next big breakthrough for restoring youthful, healthy skin.
At The Éterne Clinic, Hiranandani Gardens, Powai, we bring this cutting-edge treatment to patients who want natural, science-backed results.
What Are Polynucleotides?
Polynucleotides are bioactive molecules derived from purified DNA fragments (often from salmon DNA) that have powerful regenerative properties.
When injected into the skin, they act as cellular messengers, stimulating repair, hydration, and collagen production. Unlike fillers that simply replace lost volume, PNs work on the quality of the skin itself.
How Do Polynucleotides Work?
- Stimulate Fibroblasts: Boost production of collagen and elastin, essential for firmness.
- Repair DNA Damage: Support healing of stressed or damaged skin.
- Hydrate Deeply: Improve skin’s water balance for plumper texture.
- Anti-Inflammatory Effect: Calm redness, sensitivity, and improve overall skin resilience.
- Regenerative Boost: Promote tissue repair at a cellular level.
Benefits of Polynucleotide Skin Rejuvenation
- Improves skin elasticity and firmness
- Restores deep hydration
- Repairs sun-damaged and stressed skin
- Reduces fine lines and wrinkles
- Strengthens skin barrier
- Suitable for under-eye hollows, face, neck, and décolletage
Many patients describe the results as looking refreshed, rested, and naturally radiant rather than “filled.”
Who Should Consider Polynucleotides?
- Men & women in their 30s–50s with early signs of ageing
- Patients with dull, dehydrated, or sun-damaged skin
- Those with sensitive skin or rosacea needing calming repair
- Individuals seeking natural rejuvenation without adding volume
- Anyone wanting a preventive anti-ageing strategy
Polynucleotides vs Fillers vs Skin Boosters
- Fillers: Add volume and contour (cheeks, lips, jawline).
- Skin Boosters: Provide hydration and glow.
- Polynucleotides: Repair, regenerate, and improve skin quality at the cellular level.
👉 In many cases, they are used together for a layered, natural approach.
Why The Éterne Clinic, Powai?
- Performed under the care of Dr. Ajara Sayyad, internationally trained dermatologist in regenerative aesthetics.
- Personalised using digital skin analysis to track results.
- Combined with complementary protocols such as PRP, exosomes, or HIFU for enhanced outcomes.